Rabbit Anti-Mouse CASP8 Active Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPC120
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Mouse Active Caspase 8 Affinity Purified polyclonal antibody. Caspase 8, a member of the caspase family, of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase 8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase 8 is able to cleave and activate downstream caspases, such as caspase 3, -6, -7 and a death agonist member of the BCL2/BCL-xL family, Bid, leading to apoptosis.
Formulation
Liquid in PBS + 50% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the 25 kDa large subunit of Caspase 8. Does not detect the full length Caspase 8.
Immunogen
Synthetic peptide corresponding to residues surrounding amino acid 392 of mouse Caspase 8
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with mouse and rat.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 707,72 €
Preis: 707,72 €
lieferbar

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