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Rabbit Anti-Mouse CASP8 Active Affinity Purified pAb

Rabbit Anti-Mouse CASP8 Active Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Specific against	Mouse
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CPC120
Targets	CASP10, CASP8, CTSB
eClass 6.1	32160702
eClass 9.0	32160702
Available
Cross-Reactivity	Reacts with mouse and rat.
Description	Rabbit Anti-Mouse Active Caspase 8 Affinity Purified polyclonal antibody. Caspase 8, a member of the caspase family, of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase 8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase 8 is able to cleave and activate downstream caspases, such as caspase 3, -6, -7 and a death agonist member of the BCL2/BCL-xL family, Bid, leading to apoptosis.
Formulation	Liquid in PBS + 50% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide corresponding to residues surrounding amino acid 392 of mouse Caspase 8
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Specificity	Detects the 25 kDa large subunit of Caspase 8. Does not detect the full length Caspase 8.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CPC120.pdf

CS-CPC120-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/23/2024