Antibodies

Rabbit Anti-Mouse Fas/Apo1 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPF105
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Mouse FAS Affinity Purified polyclonal antibody. Fas/Apo1 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic “death domain” that is, responsible for transmitting signal for apoptosis.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thiomersal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects a 55 kDa form of glycosylated Fas, a 35 kDa native form of Fas, and a 29 kDa form of cleaved Fas fragment on SDS-PAGE immunoblots.
Immunogen
Synthetic peptide corresponding to residues surrounding amino acid 32 of mouse Fas.
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with human, mouse, and rat

Arbeitsanleitung

CS-CPF105.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 659,19 €
Preis: 659,19 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de