Antibodies

Mouse Anti-Rat IL-10 Clone 2G101H7 mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Rat
Clon 2G101H7
Isotype IgG1
Applikationen WB, FC, DB
Menge 0.5 mg
Host Mouse
ArtNr CS-CMI170
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western blot and dot blot analysis: Use 0.1-1.0 ug of antibody. Flow Cytometry: Use 0.1-1.0 ug per 106 cells to detect intracellular IL-10 in stimulated rat peritoneal macrophages. The optimal antibody concentration should be determined for each specific application.
Description
Mouse Anti-Rat IL-10 Clone 2G101H7 monoclonal antibody. IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. It has pleiotropic effects in immunoregulation and inflammation. IL-10 down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. It can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggest that IL-10 is an essential immunoregulator in the intestinal tract.
Formulation
Purified immunoglobulin in phosphate buffered saline, pH 7.2, carrier and preservative free. Sterile filtered through a 0.22 micron filter.
Specificity
Recognizes recombinant and native rat IL-10
Immunogen
Recombinant rat IL-10
Purification
Purified from ascites by Protein G affinity chromatography
Storage and Stability
Store at -20C. Centrifuge vial prior to opening. Upon initial thawing, aliquot into small volumes and store at -20C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Concentration
1.0 mg/ml
Purity
>95% as determined by SDS-PAGE analysis
Menge: 0.5 mg
Lieferbar: In stock
Listenpreis: 610,67 €
Preis: 610,67 €
lieferbar

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