Antibodies

Rabbit Anti-Rat TYROBP/DAP12 pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Rat
Isotype IgG
Applikationen WB
Menge 200 ug
Host Rabbit
ArtNr CS-CPD001
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western blot: working dilution of 1:1, 000. The optimal concentration should be determined by the user for each specific application.
Description
DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is a disulfide-bonded homodimer. Crosslinking of DAP12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.
Formulation
Lyophilized with 0.1% sodium azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Rat DAP12
Immunogen
Recombinant DAP12 peptide (amino acids 28-40)
Purification
Protein G purified
Reconstitution
Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 ul PBS.
Storage and Stability
4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with both recombinant and natural rat DAP12. Cross-reactivity to DAP12 of other species has not been determined.

Arbeitsanleitung

CS-CPD001.pdf

Menge: 200 ug
Lieferbar: In stock
Listenpreis: 404,42 €
Preis: 404,42 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de