Comparison

Rabbit Anti-Rat TYROBP/DAP12 pAb

Item no. CS-CPD001
Manufacturer Cell Sciences
Amount 200 ug
Category
Type Antibody Polyclonal
Applications WB
Specific against Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products DAP12, Karap, killer cell activating receptor-associated protein
Available
Manufacturer - Category
Antibodies
Storage Conditions
4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with both recombinant and natural rat DAP12. Cross-reactivity to DAP12 of other species has not been determined.
Description
DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is a disulfide-bonded homodimer. Crosslinking of DAP12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.
Formulation
Lyophilized with 0.1% sodium azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen
Recombinant DAP12 peptide (amino acids 28-40)
Purification
Protein G purified
Reconstitution
Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 ul PBS.
Specificity
Rat DAP12

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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