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Rabbit Anti-rat FasL Affinity Purified pAb

ArtNr CS-CPF107
Hersteller Cell Sciences
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Fasl, CD95-L, Tnfsf6, Apt1Lg1
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Storage Conditions
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Detects ca.31 kDa FasL in samples of mouse and rat origins. A ca.70 kDa band, possible represents the FasL and Fas complex can also be detectedThe optimal concentration should be determined by the user for each specific application.
Cross-Reactivity
Reacts with both mouse and rat.
Description
Fas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic “death domain” that is responsible for transmitting signal for apoptosis.
Formulation
Liquid in 100 ug (0.5 mg/ml) affinity purified rabbit anti-FasL polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. Precaution: Thiomersal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen
Synthetic peptide mapping to the C-terminus of rat FASLG
Purification
Affinity Purified
Specificity
Detects ca.31 kDa FASLG in samples of mouse and rat origins. A ca.70 kDa band, possibly representing the FASLG and Fas complex can also be detected.
Concentration
0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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