ArtNr |
CS-CPF107 |
Hersteller |
Cell Sciences
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Fasl, CD95-L, Tnfsf6, Apt1Lg1 |
Lieferbar |
|
Storage Conditions |
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles. |
Application Notes |
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Detects ca.31 kDa FasL in samples of mouse and rat origins. A ca.70 kDa band, possible represents the FasL and Fas complex can also be detectedThe optimal concentration should be determined by the user for each specific application. |
Cross-Reactivity |
Reacts with both mouse and rat. |
Description |
Fas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic “death domain” that is responsible for transmitting signal for apoptosis. |
Formulation |
Liquid in 100 ug (0.5 mg/ml) affinity purified rabbit anti-FasL polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. Precaution: Thiomersal is a poisonous and hazardous substance which should be handled by trained staff only. |
Immunogen |
Synthetic peptide mapping to the C-terminus of rat FASLG |
Purification |
Affinity Purified |
Specificity |
Detects ca.31 kDa FASLG in samples of mouse and rat origins. A ca.70 kDa band, possibly representing the FASLG and Fas complex can also be detected. |
Concentration |
0.5 mg/ml |
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