Antibodies

Rabbit Anti-Rat TLR4 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Rat
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPT114
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Rat TLR4 Affinity Purified polyclonal antibody. TLR4 is a mammalian homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL1 receptor for signal transduction that leads to activation of NF-eB.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Recognizes ca.92 kDa rat TLR4
Immunogen
Synthetic peptide corresponding to residues surrounding amino acids 819 or rat TLR4
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Concentration
0.5 mg/ml
Application Notes
For Western Blot use a working dilution of 0.5-4 ug/ml.The optimal concentration should be determined by the user for each specific application.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 764,71 €
Preis: 764,71 €
lieferbar

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Arbeitsanleitung

CS-CPT114.pdf