|
Hersteller |
Cell Sciences |
|
Kategorie |
|
|
Typ |
Antibody |
|
Specific against |
Rat |
|
Isotype |
IgG |
|
Applikationen |
WB |
|
Menge |
100 ug |
|
Host |
Rabbit |
|
ArtNr |
CS-CPU101 |
|
Eclass 6.1 |
32160702 |
|
Eclass 9.0 |
32160702 |
|
Lieferbar |
 |
| Applications |
Western Blot |
| Description |
Rabbit Anti-Rat PLAUR Affinity Purified polyclonal antibody. PLAUR is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (PLAU). Upon binding to PLAUR, PLAU converts the surface bound, large serum a-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. PLAU and PLAUR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis. |
| Formulation |
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only. |
| Specificity |
Recognizes 33 kDa rat PLAUR |
| Immunogen |
Synthetic peptide surrounding amino acid 51 of rat PLAUR |
| Purification |
Biospecific affinity chromatography |
| Storage and Stability |
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles. |
| Concentration |
0.5 mg/ml |
| Cross-Reactivity |
Other species not tested. |
| Application Notes |
For Western Blot, use a working dilution of 0.5-1.0 ug/ml.Blocking Peptide (Cat. No. CPU101BP) is available separately.The optimal concentration should be determined by the user for each specific application. |
