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Recombinant Human proIGF2 (aa 1-156) Receptor Grade

Recombinant Human proIGF2 (aa 1-156) Receptor Grade

Hersteller	Cell Sciences
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Carcinoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Endocrine Regulation of Lipid Metabolism
Typ	Proteins
Specific against	Human
Menge	100 ug
Host	E.coli
ArtNr	CS-AHU100
Targets	IGF2, IGF1, INS
eClass 6.1	34160400
eClass 9.0	42020190
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Biological Activity	Stimulation of protein synthesis in rat L6 myoblasts.
Description	Recombinant Human Insulin-like Growth Factor-II (Human IGF-II) is synthesized as a 156 amino acid precursor protein, known as proIGF-II. This protein includes an 87 amino acid C-terminal region known as the E-domain. A proteolysis step releases the mature 67 amino acid IGF-II polypeptide. The proIGF-II proteins make up 10-20% of circulating IGF-II. Pro-IGF-II proteins are secreted by some tumor cell lines and levels are elevated in non-islet cell tumor hypoglycemia.
Endotoxin Level	< 0.1 EU/ug
Formulation	Lyophilized white powder. Dried from 0.1 M acetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa)
Molecular Weight	The final product contains three major isoforms of proIGF-II corresponding to molecular weights of 16.1, 17.0 and 17.6 kDa. These species correspond to the full length 156 amino acid protein and two smaller species corresponding to C-terminal truncations of approximately 5 and 15 residues which result from the purification process
Reconstitution	Protocol #1000
Storage and Stability	This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

CS-AHU100.pdf

CS-AHU100-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 16.05.2024

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