Recombinant Human MYL2 (aa 1-166) His

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -80C. Avoid repeated freezing and thawing cycles.

Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. Recombinant human MYL2 protein, fused to His-tag at N-terminus, was expressed in, E. coli, and purified by using conventional chromatography techniques.

0.5 mg/ml (determined by Bradford assay)