Vergleich

Recombinant Human TDO2 T7

ArtNr CS-CRT110
Hersteller Cell Sciences
Menge 50 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products TPH2, TDO, TRPO, TO
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Store at -80C. As with any protein, exposing TDO2 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. During shipment, small volumes of TDO2 recombinant protein will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 uL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap
Molecular Weight
46.7 kDa (Calculated)
Description
The tetramer binds two molecules of protoheme IV. It is a homotetramer involved in tryptophan catabolism. There is a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of anti tumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.
Formulation
10 mM Tris + pH 8.0 + 0.1% Triton X-100 + 0.002% NaN3 + 10 mM DTT Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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