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Recombinant Human VEGF 165

ArtNr CS-CRV000B
Hersteller Cell Sciences
Menge 10 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity >95.0% by HPLC and SDS-PAGE
Sequence APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products VEGF, VPF, RP1-261G23.1, MGC70609, MVCD1, vascular permeability factor, vascular endothelial growth factor A, OTTHUMP00000165987, OTTHUMP00000224107
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
This lyophilized preparation is stable at 2-8C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
Molecular Weight
38.2 kDa
Description
Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF 165 is a disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Formulation
Lyophilized from a 0.2 um sterile filtered solution in PBS, pH 7.4
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.
Specificity
1.3 X 10E5 IU/mg
Biological Activity
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using human umbilical vein endothelial cells (HUVEC) is less than 8 ng/ml.
Endotoxin Level
Less than 1EU/ug as determined by LAL method.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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