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Recombinant Human VEGF 165

Recombinant Human VEGF 165

Manufacturer	Cell Sciences
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Adenocarcinoma By Organ Bladder Cancer
Type	Proteins
Specific against	Human
Amount	10 ug
Host	E.coli
Item no.	CS-CRV000B
Targets	VEGFA
eClass 6.1	34160400
eClass 9.0	42020190
Available
Biological Activity	Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using human umbilical vein endothelial cells (HUVEC) is less than 8 ng/ml.
Description	Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF 165 is a disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Endotoxin Level	Less than 1EU/ug as determined by LAL method.
Formulation	Lyophilized from a 0.2 um sterile filtered solution in PBS, pH 7.4
Molecular Weight	38.2 kDa
Reconstitution	Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.
Storage and Stability	This lyophilized preparation is stable at 2-8C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
Specificity	1.3 X 10E5 IU/mg

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.