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Recombinant Human UE21 His

ArtNr CS-CSI10683
Hersteller Cell Sciences
Menge 50 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag His
Purity > 95.0% as determined by RP-HPLC and SDS-PAGE.
Sequence MHHHHHHAMG TLNMSGIALS RLAQERKAWR KDHPFGFVAV PTKNPDGTMN LMNWECAIPG KKGTPWEGGL FKLRMLFKDD YPSSPPKCKF EPPLFHPNVY PSGTVCLSIL EEDKDWRPAI TIKQILLGIQ ELLNEPNIQD PAQAEAYTIY CQNRVEYEKR VRAQAKKFAP S.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products UBC9, P18, ubiquitin carrier protein, C358B7.1, SUMO-1-protein ligase, ubiquitin conjugating enzyme 9, ubiquitin-conjugating enzyme E2I, ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9), ubiquitin-conjugating enzyme UbcE2A, ubiquitin-like protein SUMO-1 conjugating enzyme, ubiquitin-protein ligase E2I
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Lyophilized UBE2I should be stored desiccated below -20C. Upon reconstitution, UBE2I may be stored at 2-4C for 1 week. For future use, store below -20C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
Molecular Weight
19.5 kDa
Description
Human Ubquitin Conjugating Enzyme 2EI is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 enzyme is unusual in that it interacts directly with protein substrates that are modified by sumolyation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, IeBa, and PML without the requirement of an E3 ligase. Recombinant Human Ubiquitin-Conjugating Enzyme E2I is a 19.5 kDa protein containing 171 amino acids. The UBE2I protein contains a 6x His tag and is purified by proprietary chromatographic techniques.
Formulation
Lyophilized from a 0.2 um filtered concentrated (1 mg/ml) solution in PBS + 1 mM DTT, pH 7.5.
Reconstitution
It is recommended to reconstitute the lyophilized UBE2I in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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