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Recombinant Human BAFF Receptor

ArtNr CS-CSI11427C
Hersteller Cell Sciences
Menge 1.0 mg
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity > 95% as determined by reduced SDS-PAGE analyses
Sequence MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products BAFFR, B-cell-activating factor receptor, BAFF receptor, BLyS receptor 3, CTA-250D10.7, BAFF-R, CD268, MGC138235, B cell-activating factor receptor, tumor necrosis factor receptor superfamily member 13C
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Manufacturer - Category
Biomolecules
Storage Conditions
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
Molecular Weight
Approximately 7.7 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.
Description
B Cell Activating Factor Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R/BAFF signaling plays a critical role in B cell survival and maturation.
Formulation
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 8.0 + 500 mM NaCl.
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.
Biological Activity
Fully biologically active when compared to standard. The ED50 determined by blocking BAFF induced mouse splenocyte survival is less than 5000 ng/ml
Endotoxin Level
Less than 1EU/ug of rHuBAFF-R as determined by LAL method.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1.0 mg
Lieferbar: In stock
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