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Recombinant Mouse M-CSF

ArtNr CS-CRM008A
Hersteller Cell Sciences
Menge 2 ug
Kategorie
Typ Proteins
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Purity >95% by SDS-PAGE and HPLC analyses.
Sequence KEVSEHCSHM IGNGHLKVLQ QLIDSQMETS CQIAFEFVDQ EQLDDPVCYL KKAFFLVQDI IDETMRFKDN TPNANATERL QELSNNLNSC FTKDYEEQNK ACVRTFHETP LQLLEKIKNF FNETKNLLEK DWNIFTKNCN NSFAKCSSRD VVTKPDCNCL YPKATPSSDP ASASPHQPPA PSMAPLAGLA WDDSQRTEGS SLLPSELPLR IEDPGSAKQR PPRSTCQTLE
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products MCSF, CSF-1, MGC31930, OTTHUMP00000013364, macrophage colony stimulating factor, OTTHUMP00000013365, RP11-195M16.2, macrophage colony-stimulating factor 1, lanimostim
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Storage Conditions
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
Molecular Weight
25.9 kDa
Description
Macrophage Colony Stimulating Factor (M-CSF), also known as CSF-1, is a four F helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. M-CSF is also essential for the survival and proliferation of osteoclast progenitors. M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis
Formulation
Lyophilized from a 0.2 um filtered solution in 20 mM Tris + 500 mM NaCl, pH7.4.
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.
Specificity
x 105 IU/mg
Biological Activity
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using mouse M-NFS-60 cells is less than 2 ng/ml.
Endotoxin Level
Less than 1EU/ug as determined by LAL method.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 2 ug
Lieferbar: In stock
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