« Zurück
Home /
Synthetic Sincalide

Synthetic Sincalide

Kein Verkauf an Patienten, Ärzte, Apotheken oder Privatpersonen! Mehr erfahren

Hersteller	Cell Sciences
Kategorie	Proteins
Typ	Proteins
Specific against	other
Menge	5 mg
ArtNr	CS-CRS140B
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Description	Sincalide also called CCK-8 has a molecular formula of C49H62N10O16S3 H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2. Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) which acts on receptors within the gallbladder wall causing it to contract. Cholecystokinin (CCK) is a hormone originally isolated from pig intestinal mucosa and described as a linear 33-amino acid peptide containing a sulfated tyrosine, which is essential for its biological activity. It has been found in mammals in both the digestive tract and the central nervous system. Among its multiple biological functions, this hormone stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility and may also act as a neurotransmitter/neuromodulator in the central nervous system.
Formulation	The Sincalide was lyophilized from a concentrated (1 mg/ml) solution with no additives.
Reconstitution	It is recommended to reconstitute the lyophilized Sincalide in sterile 18MU-cm water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions
Storage and Stability	Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CCK-8 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight	1143.29 Dalton
Purity	Greater than 98.0% as determined by analysis by RP-HPLC and Mass Spectral Anaylsis (MALDI-TOF exhibits correct Mw).

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt und Sicherheitsdatenblatt) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.