Vergleich

Synthetic Sincalide

ArtNr CS-CRS140B
Hersteller Cell Sciences
Menge 5 mg
Kategorie
Typ Proteins
Specific against other
Purity Greater than 98.0% as determined by analysis by RP-HPLC and Mass Spectral Anaylsis (MALDI-TOF exhibits correct Mw).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CCK-8 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight
1143.29 Dalton
Description
Sincalide also called CCK-8 has a molecular formula of C49H62N10O16S3 H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2. Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) which acts on receptors within the gallbladder wall causing it to contract. Cholecystokinin (CCK) is a hormone originally isolated from pig intestinal mucosa and described as a linear 33-amino acid peptide containing a sulfated tyrosine, which is essential for its biological activity. It has been found in mammals in both the digestive tract and the central nervous system. Among its multiple biological functions, this hormone stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility and may also act as a neurotransmitter/neuromodulator in the central nervous system.
Formulation
The Sincalide was lyophilized from a concentrated (1 mg/ml) solution with no additives.
Reconstitution
It is recommended to reconstitute the lyophilized Sincalide in sterile 18MU-cm water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 mg
Lieferbar: In stock
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