Fluoresceinamine-labeled Sodium Chondroitin Sulfate C

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan composed of repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and D-glucuronic acid (GlcUA). CS is abundant in cartilage and exists as unbranched polysaccharide chains covalently linked to the protein core of proteoglycans. Chondroitin sulfate C (CS-C) contains approximately one sulfate group per disaccharide unit with about 70% as 6-O-sulfation (C structure unit) and about 30% as 4-O-sulfation of GalNAc (A structure unit). This product is prepared by the fluorescent labeling of CS-C derived from shark cartilage according to the method of Ogamo et al.(1) Fluoresceinamine molecules are chemically attached to carboxyl groups of the GlcUA of CS. The excitation wavelength is 490~500 nm and the emission wavelength is 515~525 nm. The enclosed Certification of Analysis lists actual values for product specifications.

Appearance: yellow green lyophilizate

CAS number of sodium chondroitin sulfate: 12678-07-8

Fluorescent probe: Fluoresceinamine

CAS number of fluorescent probe: 3326-34-9