Fluoresceinamine-labeled Sodium Chondroitin Sulfate E

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan composed of repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and D-glucuronic acid (GlcUA). CS is abundant in cartilage and exists as unbranched polysaccharide chains covalently linked to the protein core of proteoglycans. Chondroitin sulfate E (CS-E) contains approximately 60 % of disaccharide units with two sulfate groups as 4-O- and 6-O-sulfation of GalNAc (E structure unit). This product is prepared by the fluorescent labeling of CS-E derived from squid cartilage according to the method of Ogamo et al.1). Fluoresceinamine molecules are chemically attached to carboxyl groups of the GlcUA of CS. The excitation wavelength is 490~500 nm and the emissionwavelength is 515~525 nm. The enclosed Certification of Analysis lists actual values for product specifications.

Appearance: yellow green lyophilizate

Source of sodium chondroitin sulfate E: Squid cartilage

Fluorescent probe: Fluoresceinamine

CAS number of fluorescent probe: 3326-34-9