Hyaluronan Binding Protein [HABP]  (Biotin Conj.)

hyaluronan purification with affinity column Hyaluronan binding protein rHABP is produced by expression induced culturing in the presence of IPTG using E.coli BL21(DE3)RIL transfected with human versican G1-domain expression vector pRK172VG1. As compared with animal-derived HABP, the high biological safety is confirmed. rHAB doesn't bind to other Glycosaminoglycan and DNA and specifically detects the hyaluronan (HA).Biotin is attached to rHAB to make the biotin-HABP.

Purpose of Use

For detection of the hyaluronan (HA)
Histochemistry and Cytochemistry
Detection of membrane-transferred hyaluronan
ELISA

Description

Versican G1 domain bind specifically to hyaluronan and doesn't bind to other glycosaminoglycan DNA.
Versican G1 domain can use probe for hyaluronan detection.

References

•  Tengblad A. et al., Biochem J. Nov1; 199(2):297-305 (1981)
•  Tengblad A. et al., Biochem J. Jan 1; 185(1):101-5 (1980)
◊  Invest. Ophthalmol. Vis. Sci., ?Aug 2011; 52: 6511 - 6521