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Recombinant Human Interleukin 4 (a. a. 130) Polypeptide

ArtNr DAG313
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Purity >98%pure (RP-HPLC and SDS-PAGE). Purified by chromatographic techniques. Productis sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BSF1,IL-4,BCGF1,BSF-1,BCGF-1,MGC79402,interleukin-4,binetrakin,pitrakinra,OTTHUMP00000066049,OTTHUMP00000066050,B cell growth factor 1,B_cell stimulatory factor 1,lymphocyte stimulatory factor 1,IL4,interleukin 4,Lymphocyte stimulatory factor 1
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Manufacturer - Applications
The ED50as determined by dose-dependent stimulation of TF-1 cells is <0.2ng/ml, corresponding to a specific activity of 5 x 106 IU/mg. Eachlaboratory should determine an optimum working titer for use in its particularapplication. Other applications have not been tested but use in such assaysshould not necessarily be excluded.
Storage Conditions
Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name
Interleukin 4
Product Overview
Recombinant Human Interleukin-4 is a single, non-glycosylated polypeptide chain containing 130 amino acids and having amolecular weight of 15, 000 Da. The sequence of the first five N-terminalamino acids was determined to be Met-His-Lys-Cys-Asp. Contains less than 1%dimers and aggregates.
Abbr
IL4 (a.a. 130)
Manufacturer - Format
Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration >=100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer
Lyophilized fromwater containing no additives
Concentration
1mg/ml (OD280nm, E0.1% =0.594) (prior to lyophilization)
Preservative
None
Gene Information - Gene Name
IL4interleukin 4 [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_000589
Gene Information - Protein Refseq
NP_000580
Gene Information - MIM
147780
Gene Information - Pathway
Allograft rejection, Asthma, Autoimmune thyroid disease, CD40/CD40L signaling, Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway
Gene Information - Function
cytokine activity, growth factor activity, interleukin-4 receptor binding, protein binding
Antigen Description
Interleukin-4, abbreviated IL-4, is a cytokine that induces differentiation of naive helperT cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cellssubsequently produce additional IL-4. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recentstudies suggest that basophils may be the effector cell. It is closelyrelated and has functions similar to Interleukin 13.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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