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Recombinant Human Interleukin 4 (a. a. 130) Polypeptide

Recombinant Human Interleukin 4 (a. a. 130) Polypeptide

Item no.	DAG313
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Peptides & Proteins Cell Biology Cell Culture Cytokines Peptides By Organ Heart & Blood Cancer Thyroid Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	>98%pure (RP-HPLC and SDS-PAGE). Purified by chromatographic techniques. Productis sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BSF1,IL-4,BCGF1,BSF-1,BCGF-1,MGC79402,interleukin-4,binetrakin,pitrakinra,OTTHUMP00000066049,OTTHUMP00000066050,B cell growth factor 1,B_cell stimulatory factor 1,lymphocyte stimulatory factor 1,IL4,interleukin 4,Lymphocyte stimulatory factor 1
Available
Manufacturer - Applications	The ED50as determined by dose-dependent stimulation of TF-1 cells is <0.2ng/ml, corresponding to a specific activity of 5 x 106 IU/mg. Eachlaboratory should determine an optimum working titer for use in its particularapplication. Other applications have not been tested but use in such assaysshould not necessarily be excluded.
Storage Conditions	Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name	Interleukin 4
Product Overview	Recombinant Human Interleukin-4 is a single, non-glycosylated polypeptide chain containing 130 amino acids and having amolecular weight of 15, 000 Da. The sequence of the first five N-terminalamino acids was determined to be Met-His-Lys-Cys-Asp. Contains less than 1%dimers and aggregates.
Abbr	IL4 (a.a. 130)
Manufacturer - Format	Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration >=100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer	Lyophilized fromwater containing no additives
Concentration	1mg/ml (OD280nm, E0.1% =0.594) (prior to lyophilization)
Preservative	None
Gene Information - Gene Name	IL4interleukin 4 [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_000589
Gene Information - Protein Refseq	NP_000580
Gene Information - MIM	147780
Gene Information - Pathway	Allograft rejection, Asthma, Autoimmune thyroid disease, CD40/CD40L signaling, Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway
Gene Information - Function	cytokine activity, growth factor activity, interleukin-4 receptor binding, protein binding
Antigen Description	Interleukin-4, abbreviated IL-4, is a cytokine that induces differentiation of naive helperT cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cellssubsequently produce additional IL-4. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recentstudies suggest that basophils may be the effector cell. It is closelyrelated and has functions similar to Interleukin 13.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/18/2025

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