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Recombinant Human Interleukin 11 (a. a 179) Polypeptide

ArtNr DAG318
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Purity >98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE).Endotoxin level is less than 0.1ng/ug (IEU/ug). Purified by chromatographictechniques. Product is sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL11,interleukin 11, AGIF, IL-11, interleukin-11, oprelvekin, adipogenesis inhibitoryfactor, IL 11, IL11_HUMAN, Oprelvekin
Lieferbar
Manufacturer - Applications
The ED50 as determined by dose-dependent stimulation ofthe proliferation of mouse 7TD1 is <10ng/ml, corresponding to a specificactivity of 1 x 105 IU/mg. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions
The lyophilized product, though stablefor 3 weeks at room temperature, is best stored at -20°C. Afterreconstitution, short term (up to 1 week) store at 2–8oC. Long term, add 0.1%HSA or BSA, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
Full name
Interleukin 11
Product Overview
RecombinantHuman IL-11 is a single, non-glycosylated polypeptide chain containing 179amino acids and having a molecular weight of 19, 256.29 Da. The sequence ofthe first five N-terminal amino acids was determined to beGly-Pro-Pro-Pro-Gly. N-terminal methionine has been completely removedenzymatically. Contains less than 1% dimers and aggregates.
Abbr
IL-11 (a.a 179)
Manufacturer - Format
Purified, Lyophilized, Reconstitute using sterile deionized water to a concentration >100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer
Not applicable
Concentration
1mg/ml (OD280nm, E0.1% = 0.95) (prior tolyophilization)
Preservative
None
Gene Information - Gene Name
IL11interleukin 11 [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_000641
Gene Information - Protein Refseq
NP_000632
Gene Information - MIM
147681
Gene Information - Pathway
Cytokine-cytokinereceptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Rheumatoid arthritis
Gene Information - Function
cytokine activity, growth factor activity, interleukin-11 receptor binding
Antigen Description
Interleukin11(IL-11) is a protein that in humans is encoded by the IL11 gene. IL-11 is amultifunctional cytokine first isolated in 1990 from bone marrow-derivedstromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. It is also knownunder the names adipogenesis inhibitory factor (AGIF) and oprelvekin.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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