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Recombinant Human Interleukin 11 (a. a 179) Polypeptide

Recombinant Human Interleukin 11 (a. a 179) Polypeptide

Item no.	DAG318
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Peptides & Proteins Obesity Peptides By Organ Heart & Blood Cancer Bone Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	>98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE).Endotoxin level is less than 0.1ng/ug (IEU/ug). Purified by chromatographictechniques. Product is sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL11,interleukin 11, AGIF, IL-11, interleukin-11, oprelvekin, adipogenesis inhibitoryfactor, IL 11, IL11_HUMAN, Oprelvekin
Available
Manufacturer - Applications	The ED50 as determined by dose-dependent stimulation ofthe proliferation of mouse 7TD1 is <10ng/ml, corresponding to a specificactivity of 1 x 105 IU/mg. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions	The lyophilized product, though stablefor 3 weeks at room temperature, is best stored at -20°C. Afterreconstitution, short term (up to 1 week) store at 2–8oC. Long term, add 0.1%HSA or BSA, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
Full name	Interleukin 11
Product Overview	RecombinantHuman IL-11 is a single, non-glycosylated polypeptide chain containing 179amino acids and having a molecular weight of 19, 256.29 Da. The sequence ofthe first five N-terminal amino acids was determined to beGly-Pro-Pro-Pro-Gly. N-terminal methionine has been completely removedenzymatically. Contains less than 1% dimers and aggregates.
Abbr	IL-11 (a.a 179)
Manufacturer - Format	Purified, Lyophilized, Reconstitute using sterile deionized water to a concentration >100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	1mg/ml (OD280nm, E0.1% = 0.95) (prior tolyophilization)
Preservative	None
Gene Information - Gene Name	IL11interleukin 11 [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_000641
Gene Information - Protein Refseq	NP_000632
Gene Information - MIM	147681
Gene Information - Pathway	Cytokine-cytokinereceptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Rheumatoid arthritis
Gene Information - Function	cytokine activity, growth factor activity, interleukin-11 receptor binding
Antigen Description	Interleukin11(IL-11) is a protein that in humans is encoded by the IL11 gene. IL-11 is amultifunctional cytokine first isolated in 1990 from bone marrow-derivedstromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. It is also knownunder the names adipogenesis inhibitory factor (AGIF) and oprelvekin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 10/9/2025

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