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Recombinant Human Interleukin 15 (a.a. 114) Polypeptide

ArtNr DAG321
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Purity >98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE).Endotoxin level is less than 0.1ng/ug (IEU/ug). Purified by chromatographictechniques. Product is sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL15,interleukin 15,IL-15,MGC9721,interleukin-15,OTTHUMP00000164616,OTTHUMP00000164617,OTTHUMP00000218093,OTTHUMP00000228804,OTTHUMP00000228805,IL15,IL15_HUMAN
Lieferbar
Manufacturer - Applications
The ED50 as determined by the dose-dependentstimulation of the proliferation of mouse CTLL-2 cells is <0.5ng/ml, corresponding to a specific activity of 2 x 106 IU/mg. Eachlaboratory should determine an optimum working titer for use in itsparticular application. Other applications have not been tested but use insuch assays should not necessarily be excluded.
Storage Conditions
The lyophilizedproduct, though stable for 3 weeks at room temperature, is best stored at–20°C. After reconstitution, short term (up to 1 week) store at 2-8oC. Longterm, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoid multiplefreeze/thaw cycles.
Full name
Interleukin 15
Product Overview
RecombinantHuman IL-15 is a single non-glycosylated polypeptide chain containing 114amino acids and having a molecular weight of 12, 773.5 Da. The sequence of thefirst five N-terminal amino acids was determined to be Met-Asn-Trp-Val-Asn.Contains less than 1% dimers and aggregates.
Abbr
IL15 (a.a. 114)
Manufacturer - Format
Purified, Lyophilized, Reconstitute using sterile deionizedwater to a concentration >100ug/ml. Further dilutions can be made in otheraqueous buffers.
Buffer
Lyophilized from water without additives
Concentration
Not applicable
Preservative
None
Gene Information - Gene Name
IL15interleukin 15 [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_000585
Gene Information - Protein Refseq
NP_000576
Gene Information - MIM
600554
Gene Information - Pathway
Cytokine-cytokinereceptor interaction, Cytokines and Inflammatory Response, HTLV-I infection, Herpes simplex infection, Intestinal immune network for IgA production, Jak-STAT signaling pathway, Rheumatoid arthritis
Gene Information - Function
cytokine activity, cytokinereceptor binding, signal transducer activity
Antigen Description
Interleukin 15 (IL-15) is acytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to andsignals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain(gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some othercells) following infection by virus(es). This cytokine induces cellproliferation of natural killer cells, cells of the innate immune systemwhose principal role is to kill virally infected cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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