Recombinant Human Laminin-5

Store at-70°C. Avoid multiple freeze/thaw cycles.

HumanLaminin-5, Recombinant. Molecular weight 450kDa. Does not contain a fusionpartner.

Purified, Liquid

Lotspecific

LAMA5 laminin, alpha 5 [ Homosapiens ]

NP_005551

Alpha6-Beta4Integrin Signaling Pathway, Amoebiasis, Focal Adhesion, Inflammatory ResponsePathway, Pathways in cancer, Small cell lung cancer, Syndecan-1-mediatedsignaling events, Toxoplasmosis

Laminin, the most abundant structural and biologically active component in basementmembranes, is a complex extracellular glycoprotein with an approximatemolecular weight of 900 kDa. It plays an important role in many aspects ofthe cell biology. Laminin is composed of one A chain (400 kDa) one B1 chain(215 kDa) and one B2 chain (205 kDa) all held together by disulfide bonds.The molecule has a cross like form with globular units near the ends of eachchain, the sites where it is bound to Collagen IV, heparan sulfate, proteoglycan as well as to the surface of epithelial cells. Laminins fromvarious species have common antigenic determinants.