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Recombinant Mouse Chemokine (C-C motif) Ligand 3 (a. a. 69), Polypeptide

ArtNr DAG288
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Purity >99%pure (HPLC, FPLC, and reducing and non-reducing SDS-PAGE). Endotoxin level isless than 0.1ng/ug (IEU/ug). Purified by chromatographic techniques.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mip1a,Scya3,G0S19-1,AI323804,MIP1-(a),LD78alpha,MIP-1alpha,MIP1-alpha,C-Cmotifchemokine 3,TY-5,L2G25B,MIP1 (a),SIS-alpha,MIP-1 alpha,MIP-1-alpha,OTTMUSP00000000942,small inducible cytokine A3,small-inducible cytokine A3,heparin-binding chemotaxis protein,macrophage inflammatory protein-1alpha,macrophage inflammatory protein 1-alpha
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Manufacturer - Applications
The activity is calculated by the ability to chemoattract Balb3/c splenocytesusing a concentration of 1–10ng/ml. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions
Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at -20 oC. After reconstitution, short term (up to 1 week) store at2–8oC. Long term, add 0.1% HSA or BSA, aliquot and store at -20°C. Avoidmultiple freeze-thaw cycles.
Full name
Chemokine (C-C motif) Ligand 3
Product Overview
Recombinantmouse MIP-1a is a single, non-glycosylated polypeptide chain containing 69amino acids and having a molecular weight of 7820 Da. The sequence of thefirst five N-terminal amino acids was determined to be Ala-Pro-Tyr-Gly-Ala.Contains less than 1% dimers and aggregates.
Abbr
Ccl3 (a.a. 69)
Manufacturer - Format
Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration>=100ug/ml. Further dilutions can be made in other aqueous buffers.
Buffer
Not applicable
Concentration
Lot specific (priorto lyophilization)
Preservative
None
Gene Information - Gene Name
Ccl3chemokine (C-C motif) ligand 3 [ Mus musculus ]
Gene Information - mRNA Refseq
NM_011337
Gene Information - Protein Refseq
NP_035467
Gene Information - Pathway
Chagas disease(American trypanosomiasis), Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Salmonella infection
Gene Information - Function
chemoattractantactivity, chemokine activity, cytokine activity, protein binding
Antigen Description
Chemokine (C-C motif) ligand 3 (CCL3) is aprotein that in humans is encoded by the CCL3 gene.CCL3, also known asMacrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to theCC chemokine family that is involved in the acute inflammatory state in therecruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988). Sherry et al. (1988) demonstrated 2 protein components of MIP1, calledby them alpha and beta.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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