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Recombinant Mouse Chemokine (C-C motif) Ligand 3 (a. a. 69), Polypeptide

Recombinant Mouse Chemokine (C-C motif) Ligand 3 (a. a. 69), Polypeptide

Item no.	DAG288
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Peptides & Proteins Peptides By Organ Heart & Blood Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	>99%pure (HPLC, FPLC, and reducing and non-reducing SDS-PAGE). Endotoxin level isless than 0.1ng/ug (IEU/ug). Purified by chromatographic techniques.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mip1a,Scya3,G0S19-1,AI323804,MIP1-(a),LD78alpha,MIP-1alpha,MIP1-alpha,C-Cmotifchemokine 3,TY-5,L2G25B,MIP1 (a),SIS-alpha,MIP-1 alpha,MIP-1-alpha,OTTMUSP00000000942,small inducible cytokine A3,small-inducible cytokine A3,heparin-binding chemotaxis protein,macrophage inflammatory protein-1alpha,macrophage inflammatory protein 1-alpha
Available
Manufacturer - Applications	The activity is calculated by the ability to chemoattract Balb3/c splenocytesusing a concentration of 1–10ng/ml. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions	Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at -20 oC. After reconstitution, short term (up to 1 week) store at2–8oC. Long term, add 0.1% HSA or BSA, aliquot and store at -20°C. Avoidmultiple freeze-thaw cycles.
Full name	Chemokine (C-C motif) Ligand 3
Product Overview	Recombinantmouse MIP-1a is a single, non-glycosylated polypeptide chain containing 69amino acids and having a molecular weight of 7820 Da. The sequence of thefirst five N-terminal amino acids was determined to be Ala-Pro-Tyr-Gly-Ala.Contains less than 1% dimers and aggregates.
Abbr	Ccl3 (a.a. 69)
Manufacturer - Format	Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration>=100ug/ml. Further dilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	Lot specific (priorto lyophilization)
Preservative	None
Gene Information - Gene Name	Ccl3chemokine (C-C motif) ligand 3 [ Mus musculus ]
Gene Information - mRNA Refseq	NM_011337
Gene Information - Protein Refseq	NP_035467
Gene Information - Pathway	Chagas disease(American trypanosomiasis), Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Salmonella infection
Gene Information - Function	chemoattractantactivity, chemokine activity, cytokine activity, protein binding
Antigen Description	Chemokine (C-C motif) ligand 3 (CCL3) is aprotein that in humans is encoded by the CCL3 gene.CCL3, also known asMacrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to theCC chemokine family that is involved in the acute inflammatory state in therecruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988). Sherry et al. (1988) demonstrated 2 protein components of MIP1, calledby them alpha and beta.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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