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Recombinant Mouse colony stimulating factor 3 (granulocyte) (a. a. 179) Polypeptide

ArtNr DAG322
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Purity >98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE).Endotoxin level is less than 0.1ng/ug (IEU/ug). Purified by chromatographictechniques. Product is sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Csf3,colonystimulating factor 3 (granulocyte),Csfg,G-CSF,MGI-IG,granulocytecolony-stimulating factor,OTTMUSP00000006785,CSF3,C17orf33,CSF3OS,GCSF,MGC45931,Colony stimulating factor 3 (granulocyte)
Lieferbar
Manufacturer - Applications
The ED50 as determined by thedose-dependent proliferation of Mouse NFS-60 indicator cells (measured byH-thymidine uptake) is <0.05ng/ml, corresponding to a specific activity of2 x 107 IU/mg. Each laboratory should determine an optimum workingtiter for use in its particular application. Other applications have not beentested but use in such assays should not necessarily be excluded.
Storage Conditions
The lyophilized product, though stablefor 3 weeks at room temperature, is best stored at -20°C. Afterreconstitution, short term (up to 1 week) store at 2–8oC. Long term, add 0.1%HSA or BSA, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
Full name
Colony Stimulating Factor 3 (Granulocyte)
Product Overview
RecombinantMouse G-CSF is a single non-glycosylated polypeptide chain containing 179amino acids and having a molecular weight of 19 kDa. The sequence of thefirst five N-terminal amino acids was determined to be Met-Val-Pro-Leu-Val.Contains less than 1% dimers and aggregates.
Abbr
Csf3 (a.a. 179)
Manufacturer - Format
Purified, Lyophilized, Reconstitute using sterile deionizedwater to a concentration >100ug/ml. Further dilutions can be made in other aqueousbuffers.
Buffer
Not applicable
Concentration
1mg/ml (prior to lyophilization) (OD280nm, E0.1% =0.51)
Preservative
None
Gene Information - Gene Name
Csf3colony stimulating factor 3 (granulocyte) [ Mus musculus ]
Gene Information - mRNA Refseq
NM_009971
Gene Information - Protein Refseq
NP_034101
Gene Information - Pathway
Cytokine-cytokinereceptor interaction, Cytokines and Inflammatory Response (BioCarta), Hematopoieticcell lineage, Jak-STAT signaling pathway
Gene Information - Function
cytokine activity, enzymebinding, growth factor activity
Antigen Description
Granulocyte colony-stimulating factor(G-CSF or GCSF) is a colony-stimulating factor hormone. G-CSF is also knownas colony-stimulating factor 3 (CSF 3). G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors andmature neutrophils. G-CSF regulates them using Janus kinase (JAK)/signaltransducer and activator of transcription (STAT) and Ras /mitogen-activatedprotein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K)/protein kinaseB (Akt) signal transduction pathway.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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