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Recombinant Human Fibroblast Growth Factor 7 (a. a. 164)

ArtNr DAG303
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity >98% pure (HPLC, FPLC and reducingand non-reducing SDS-PAGE). Endotoxin level is less than 0.1ng/ug (IEU/ug).Purified by chromatographic techniques. Product is sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FGF7,fibroblastgrowth factor 7,KGF,HBGF-7,keratinocyte growth factor,OTTHUMP00000162252,heparin-binding growth factor 7,HBGF 7,HBGF7,FGF 7,FGF-7,FibroblastGrowth Factor 7,Keratinocyte Growth Factor,Heparin binding growth factor 7
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Manufacturer - Applications
The ED50 as determined by thedose-dependent stimulation of KGF-responsive BaF3 indicator cells (measuredby 3H-thymidine uptake) is <10ng/ml, corresponding to aspecific activity of 10 Units/mg. Each laboratory should determine an optimumworking titer for use in its particular application. Other applications havenot been tested but use in such assays should not necessarily be excluded.
Storage Conditions
Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name
Fibroblast Growth Factor 7
Product Overview
RecombinantHuman FGF7 is a single, non-glycosylated, polypeptide chain containing 164amino acids and having a molecular weight of 18, 995 Da, was expressed in E.coli. The sequence of the first five N-terminal amino acids was determined tobe Met-Cys-Asn-Asp-Met. Contains less than 1% dimers and aggregates.
Abbr
FGF7 (a.a. 164)
Manufacturer - Format
Purified, Lyophilized. Reconstituteusing sterile deionized water to a concentration >100ug/ml. Furtherdilutions can be made in other aqueous buffers.
Buffer
Not applicable
Concentration
1mg/ml(OD280nm, E0.1% = 0.9) (prior to lyophilization)
Preservative
None
Gene Information - Gene Name
FGF7fibroblast growth factor 7 [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_002009
Gene Information - Protein Refseq
NP_002000
Gene Information - MIM
148180
Gene Information - Pathway
Downstream signalingof activated FGFR, FGFR ligand binding and activation, FGFR2 ligand bindingand activation, IRS-related events, MAPK signaling pathway, PI-3K cascade, Pathways in cancer, Regulation of actin cytoskeleton
Gene Information - Function
chemoattractantactivity, growth factor activity, heparin binding, type 2 fibroblast growthfactor receptor binding
Antigen Description
The Keratinocyte Growth Factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phaseof wound healing. In this phase, keratinocytes are covering the wound, forming the epithelium. KGF is a small signaling molecule that binds tofibroblast growth factor receptor 2b (FGFR2b). For signalling to occur, adimer is required between two FGF:FGFR complexes that is linked together by amolecule of heparin.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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