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Recombinant Human Fibroblast Growth Factor 7 (a. a. 164)

Recombinant Human Fibroblast Growth Factor 7 (a. a. 164)

Item no.	DAG303
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins By Organ Lung Cancer Heart & Blood Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	>98% pure (HPLC, FPLC and reducingand non-reducing SDS-PAGE). Endotoxin level is less than 0.1ng/ug (IEU/ug).Purified by chromatographic techniques. Product is sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FGF7,fibroblastgrowth factor 7,KGF,HBGF-7,keratinocyte growth factor,OTTHUMP00000162252,heparin-binding growth factor 7,HBGF 7,HBGF7,FGF 7,FGF-7,FibroblastGrowth Factor 7,Keratinocyte Growth Factor,Heparin binding growth factor 7
Available
Manufacturer - Applications	The ED50 as determined by thedose-dependent stimulation of KGF-responsive BaF3 indicator cells (measuredby 3H-thymidine uptake) is <10ng/ml, corresponding to aspecific activity of 10 Units/mg. Each laboratory should determine an optimumworking titer for use in its particular application. Other applications havenot been tested but use in such assays should not necessarily be excluded.
Storage Conditions	Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name	Fibroblast Growth Factor 7
Product Overview	RecombinantHuman FGF7 is a single, non-glycosylated, polypeptide chain containing 164amino acids and having a molecular weight of 18, 995 Da, was expressed in E.coli. The sequence of the first five N-terminal amino acids was determined tobe Met-Cys-Asn-Asp-Met. Contains less than 1% dimers and aggregates.
Abbr	FGF7 (a.a. 164)
Manufacturer - Format	Purified, Lyophilized. Reconstituteusing sterile deionized water to a concentration >100ug/ml. Furtherdilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	1mg/ml(OD280nm, E0.1% = 0.9) (prior to lyophilization)
Preservative	None
Gene Information - Gene Name	FGF7fibroblast growth factor 7 [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_002009
Gene Information - Protein Refseq	NP_002000
Gene Information - MIM	148180
Gene Information - Pathway	Downstream signalingof activated FGFR, FGFR ligand binding and activation, FGFR2 ligand bindingand activation, IRS-related events, MAPK signaling pathway, PI-3K cascade, Pathways in cancer, Regulation of actin cytoskeleton
Gene Information - Function	chemoattractantactivity, growth factor activity, heparin binding, type 2 fibroblast growthfactor receptor binding
Antigen Description	The Keratinocyte Growth Factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phaseof wound healing. In this phase, keratinocytes are covering the wound, forming the epithelium. KGF is a small signaling molecule that binds tofibroblast growth factor receptor 2b (FGFR2b). For signalling to occur, adimer is required between two FGF:FGFR complexes that is linked together by amolecule of heparin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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