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Recombinant Human Oncostatin M (a. a. 227)

ArtNr DAG349
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity >98% pure (SDS-PAGE and HPLC analysis). Endotoxin level is<0.1ng per ug (1EU/ug). Product is 0.2um filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias OSM, oncostatin M,MGC20461, oncostatin-M, OTTHUMP00000198700, ONCM, Oncostatin M precursor,Oncostatin-M
Lieferbar
Manufacturer - Applications
The ED50 as determined by the dose-dependent stimulationof the proliferation of human TF-1 cells is <2ng/ml, correspondingto a specific activity of >5 x 105 units/mg. Eachlaboratory should determine an optimum working titer for use in itsparticular application. Other applications have not been tested but use insuch assays should not necessarily be excluded.
Storage Conditions
The lyophilized product is stable for a few weeks at roomtemperature but is best stored at –20°C. After reconstitution, aliquot andstore at –20°C.
Full name
Oncostatin M
Product Overview
Human Oncostatin M Oncostatin is an important growth regulatingcytokine that affects, variably, a number of tumor and normal cells. HumanOncostatin M is a 26 kDa protein containing 227 amino acid residues, and wasexpressed in E. coli.
Abbr
OSM
Manufacturer - Format
Purified, Lyophilized. We recommend a quick spin followed byreconstitution in water to a concentration of 0.1-1.0mg/ml. This solution canthen be diluted into other aqueous buffers and stored at 2-8C for up to oneweek or –20C for future use.
Buffer
Not applicable
Concentration
Not applicable
Preservative
None
Gene Information - Gene Name
OSMoncostatin M [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_020530
Gene Information - Protein Refseq
NP_065391
Gene Information - MIM
165095
Gene Information - Pathway
Adipogenesis, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Information - Function
cytokineactivity, growth factor activity, oncostatin-M receptor binding
Antigen Description
OSM is apleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Ofthese cytokines it most closely resembles leukemia inhibitory factor (LIF) inboth structure and function. However, it is as yet poorly defined and isproving important in liver development, haematopoeisis, inflammation andpossibly CNS development. It is also associated with bone formation anddestruction

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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