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Recombinant Human Oncostatin M (a. a. 227)

Recombinant Human Oncostatin M (a. a. 227)

Item no.	DAG349
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity By Organ Heart & Blood Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	>98% pure (SDS-PAGE and HPLC analysis). Endotoxin level is<0.1ng per ug (1EU/ug). Product is 0.2um filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	OSM, oncostatin M,MGC20461, oncostatin-M, OTTHUMP00000198700, ONCM, Oncostatin M precursor,Oncostatin-M
Available
Manufacturer - Applications	The ED50 as determined by the dose-dependent stimulationof the proliferation of human TF-1 cells is <2ng/ml, correspondingto a specific activity of >5 x 105 units/mg. Eachlaboratory should determine an optimum working titer for use in itsparticular application. Other applications have not been tested but use insuch assays should not necessarily be excluded.
Storage Conditions	The lyophilized product is stable for a few weeks at roomtemperature but is best stored at –20°C. After reconstitution, aliquot andstore at –20°C.
Full name	Oncostatin M
Product Overview	Human Oncostatin M Oncostatin is an important growth regulatingcytokine that affects, variably, a number of tumor and normal cells. HumanOncostatin M is a 26 kDa protein containing 227 amino acid residues, and wasexpressed in E. coli.
Abbr	OSM
Manufacturer - Format	Purified, Lyophilized. We recommend a quick spin followed byreconstitution in water to a concentration of 0.1-1.0mg/ml. This solution canthen be diluted into other aqueous buffers and stored at 2-8C for up to oneweek or –20C for future use.
Buffer	Not applicable
Concentration	Not applicable
Preservative	None
Gene Information - Gene Name	OSMoncostatin M [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_020530
Gene Information - Protein Refseq	NP_065391
Gene Information - MIM	165095
Gene Information - Pathway	Adipogenesis, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Information - Function	cytokineactivity, growth factor activity, oncostatin-M receptor binding
Antigen Description	OSM is apleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Ofthese cytokines it most closely resembles leukemia inhibitory factor (LIF) inboth structure and function. However, it is as yet poorly defined and isproving important in liver development, haematopoeisis, inflammation andpossibly CNS development. It is also associated with bone formation anddestruction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 10/9/2025

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