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Recombinant Human KIT Ligand (a. a. 165)

ArtNr DAG357
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity >98%pure (SDS-PAGE and HPLC analysis). Endotoxin level is less than 0.1ng per ugof SCF. Product is 0.2um filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias KITLG,KIT ligand,SF,MGF,SCF,FPH2,KL-1,Kitl,SHEP7,kit-ligand,DKFZp686F2250,c-Kitligand,steel factor,stem cell factor,mast cell growth factor,familialprogressive hyperpigmentation 2,C kit ligand,C-kit ligand,Ckit ligand,KL1,KL1,sKITLG,Soluble KIT ligand,Stem cell factor precursor
Lieferbar
Manufacturer - Applications
The ED50as determined by the dose-dependent stimulation of TF-1 cells was foundto be< 2.0ng/ml, corresponding to a specific activity of >5x105units/mg. Each laboratory should determine an optimum working titer for usein its particular application. Other applications have not been tested butuse in such assays should not necessarily be excluded.
Storage Conditions
Thelyophilized SCF, though stable at room temperature, is best stored desiccatedbelow 0C C. After reconstitution, aliquot and store at –20°C.
Full name
KIT Ligand
Product Overview
Ahematopoietic growth factor that exerts its activity at the early stages ofhematopoiesis. KITLG stimulates the proliferation of myeloid, erythroid, andlymphoid progenitors in bone marrow cultures and has been shown to actsynergistically with colony stimulating factors. Human KITLG which wasexpressed in E. coli is an 18.4kDa protein containing 165 amino acidresidues.
Abbr
KITLG (a.a. 165)
Manufacturer - Format
Purified, Lyophilized. Reconstitute in 10mM Acetic Acid to a concentration of0.1-1.0mg/ml. This solution can be diluted into water or other bufferedsolutions or stored at –20C C for future use.
Buffer
Not applicable
Concentration
Not applicable
Preservative
None
Gene Information - Gene Name
KITLGKIT ligand [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_000899
Gene Information - Protein Refseq
NP_000890
Gene Information - MIM
184745
Gene Information - Pathway
C-MYB transcriptionfactor network, Cytokine-cytokine receptor interaction, Signaling eventsmediated by Stem cell factor receptor (c-Kit), Melanogenesis, Hematopoieticcell lineageKit Receptor Signaling Pathway
Gene Information - Function
cytokine activity, growth factor activity, protein binding, stem cell factor receptor binding
Antigen Description
StemCell Factor (also known as SCF, kit-ligand, KL, or steel factor) is acytokine that binds to the c-Kit receptor (CD117). SCF can exist both as atransmembrane protein and a soluble protein. This cytokine plays an importantrole in hematopoiesis (formation of blood cells), spermatogenesis, andmelanogenesis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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