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Recombinant Human KIT Ligand (a. a. 165)

Recombinant Human KIT Ligand (a. a. 165)

Item no.	DAG357
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Lung Cancer Bone Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	>98%pure (SDS-PAGE and HPLC analysis). Endotoxin level is less than 0.1ng per ugof SCF. Product is 0.2um filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KITLG,KIT ligand,SF,MGF,SCF,FPH2,KL-1,Kitl,SHEP7,kit-ligand,DKFZp686F2250,c-Kitligand,steel factor,stem cell factor,mast cell growth factor,familialprogressive hyperpigmentation 2,C kit ligand,C-kit ligand,Ckit ligand,KL1,KL1,sKITLG,Soluble KIT ligand,Stem cell factor precursor
Available
Manufacturer - Applications	The ED50as determined by the dose-dependent stimulation of TF-1 cells was foundto be< 2.0ng/ml, corresponding to a specific activity of >5x105units/mg. Each laboratory should determine an optimum working titer for usein its particular application. Other applications have not been tested butuse in such assays should not necessarily be excluded.
Storage Conditions	Thelyophilized SCF, though stable at room temperature, is best stored desiccatedbelow 0C C. After reconstitution, aliquot and store at –20°C.
Full name	KIT Ligand
Product Overview	Ahematopoietic growth factor that exerts its activity at the early stages ofhematopoiesis. KITLG stimulates the proliferation of myeloid, erythroid, andlymphoid progenitors in bone marrow cultures and has been shown to actsynergistically with colony stimulating factors. Human KITLG which wasexpressed in E. coli is an 18.4kDa protein containing 165 amino acidresidues.
Abbr	KITLG (a.a. 165)
Manufacturer - Format	Purified, Lyophilized. Reconstitute in 10mM Acetic Acid to a concentration of0.1-1.0mg/ml. This solution can be diluted into water or other bufferedsolutions or stored at –20C C for future use.
Buffer	Not applicable
Concentration	Not applicable
Preservative	None
Gene Information - Gene Name	KITLGKIT ligand [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_000899
Gene Information - Protein Refseq	NP_000890
Gene Information - MIM	184745
Gene Information - Pathway	C-MYB transcriptionfactor network, Cytokine-cytokine receptor interaction, Signaling eventsmediated by Stem cell factor receptor (c-Kit), Melanogenesis, Hematopoieticcell lineageKit Receptor Signaling Pathway
Gene Information - Function	cytokine activity, growth factor activity, protein binding, stem cell factor receptor binding
Antigen Description	StemCell Factor (also known as SCF, kit-ligand, KL, or steel factor) is acytokine that binds to the c-Kit receptor (CD117). SCF can exist both as atransmembrane protein and a soluble protein. This cytokine plays an importantrole in hematopoiesis (formation of blood cells), spermatogenesis, andmelanogenesis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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