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Recombinant Mouse GRO-alpha/KC (CXCL1)

ArtNr DAG286
Hersteller Creative Diagnostics
Menge 20 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity >95%pure (RP-HPLC and SDS-PAGE). Purified by chromatographic techniques. Productis sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias KC,Fsp,N51,gro,Gro1,Mgsa,Scyb1,growth-regulated alpha protein,KC/GR)-alpha,KC/GRO-alpha,GRO1 oncogene,OTTMUSP00000018305,secretory protein N51,C-X-C motif chemokine 1,platelet-derived growthfactor-inducible protein KC
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Manufacturer - Applications
Thebiological activity was determined by measuring the dose dependentmobilization of intracellular calcium (calcium flux) with human neutrophils.Significant calcium mobilization is observed with >=50ng/ml of recombinantmouse KC (Specific Activity: >=2 x 104 units/mg). Each laboratoryshould determine an optimum working titer for use in its particularapplication. Other applications have not been tested but use in such assaysshould not necessarily be excluded.
Storage Conditions
Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Product Overview
RecombinantMouse KC also known as N51 and GRO-1 is a single, non-glycosylatedpolypeptide chain containing 77 amino acids and having a molecular weight of8 kDa. Sequence: RLATGAPIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREACLDPEAPLVQ KIVQKMLKGV PK
Abbr
Cxcl1 (Mouse)
Manufacturer - Format
Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration>100ug/ml. Further dilutions can be made in other aqueous buffers.
Buffer
Not applicable
Concentration
1mg/ml(OD280nm, E0.1% = 0.03) (prior to lyophilization)
Preservative
None
Gene Information - Gene Name
Cxcl1chemokine (C-X-C motif) ligand 1 [ Mus musculus ]
Gene Information - mRNA Refseq
NM_008176
Gene Information - Protein Refseq
NP_032202
Gene Information - Pathway
Chemokine receptorsbind chemokines, Chemokine signaling pathway, Cytokine-cytokine receptorinteraction, Cytokines and Inflammatory Response (BioCarta), GPCR ligand binding, Legionellosis, NOD-like receptor signaling pathway, Salmonella infection, Signaling by GPCR
Gene Information - Function
chemokine activity, cytokine activity, growth factor activity
Antigen Description
Has chemotactic activity for neutrophils. May play a rolein inflammation and exerts its effects on endothelial cells in an autocrinefashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) andGRO-alpha(6-73) show a 30-fold higher chemotactic activity.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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