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Recombinant Mouse GRO-alpha/KC (CXCL1)

Recombinant Mouse GRO-alpha/KC (CXCL1)

Item no.	DAG286
Manufacturer	Creative Diagnostics
Amount	20 ug
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Skin Cancer Heart & Blood Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	>95%pure (RP-HPLC and SDS-PAGE). Purified by chromatographic techniques. Productis sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KC,Fsp,N51,gro,Gro1,Mgsa,Scyb1,growth-regulated alpha protein,KC/GR)-alpha,KC/GRO-alpha,GRO1 oncogene,OTTMUSP00000018305,secretory protein N51,C-X-C motif chemokine 1,platelet-derived growthfactor-inducible protein KC
Available
Manufacturer - Applications	Thebiological activity was determined by measuring the dose dependentmobilization of intracellular calcium (calcium flux) with human neutrophils.Significant calcium mobilization is observed with >=50ng/ml of recombinantmouse KC (Specific Activity: >=2 x 104 units/mg). Each laboratoryshould determine an optimum working titer for use in its particularapplication. Other applications have not been tested but use in such assaysshould not necessarily be excluded.
Storage Conditions	Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Product Overview	RecombinantMouse KC also known as N51 and GRO-1 is a single, non-glycosylatedpolypeptide chain containing 77 amino acids and having a molecular weight of8 kDa. Sequence: RLATGAPIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREACLDPEAPLVQ KIVQKMLKGV PK
Abbr	Cxcl1 (Mouse)
Manufacturer - Format	Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration>100ug/ml. Further dilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	1mg/ml(OD280nm, E0.1% = 0.03) (prior to lyophilization)
Preservative	None
Gene Information - Gene Name	Cxcl1chemokine (C-X-C motif) ligand 1 [ Mus musculus ]
Gene Information - mRNA Refseq	NM_008176
Gene Information - Protein Refseq	NP_032202
Gene Information - Pathway	Chemokine receptorsbind chemokines, Chemokine signaling pathway, Cytokine-cytokine receptorinteraction, Cytokines and Inflammatory Response (BioCarta), GPCR ligand binding, Legionellosis, NOD-like receptor signaling pathway, Salmonella infection, Signaling by GPCR
Gene Information - Function	chemokine activity, cytokine activity, growth factor activity
Antigen Description	Has chemotactic activity for neutrophils. May play a rolein inflammation and exerts its effects on endothelial cells in an autocrinefashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) andGRO-alpha(6-73) show a 30-fold higher chemotactic activity.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 12/25/2025

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