Recombinant Hepatitis B Surface Antigen (ayw)

Store at 2–8oC. DO NOT FREEZE!

Recombinant, Hepatitis B surface antigen, contains full-length HBsAg (226 amino acids, molecular weight of 25.5 kDa), was, expressed in Pichia pastoris, and puried in vitro using Metal affinity, chromatography techniques.

HBsAg, Hep B surface antigen, Hepatitis B Virus major surface antigen, Hepatitis B, virus S antigen, Large envelope protein, Large surface protein, LHB, Major, surface antigen, Hepadnaviridae, Orthohepadnavirus

Purified, Liquid

1mg/ml

HBsAg is the surface, antigen of the Hepatitis-B-Virus (HBV). It indicates current Hepatitis B, infection. The capsid of a virus has different surface proteins from the rest of the, virus which act as antigens. These antigens are recognized by antibody, proteins that bind specifically to one of these surface proteins. Today, these antigen-proteins can be a genetically manufactured (e.g. transgene E. coli) to produce material for a simple antigen test, which detects the, presence of HBV. It is present in the sera of patients with viral hepatitis B, (with or without clinical symptoms). Patients who developed antibodies, against HBsAg (anti-HBsAg seroconversion) are usually considered, non-infectious. HBsAg detection by immunoassay is used in blood screening, to, establish a diagnosis of hepatitis B infection in the clinical setting (in, combination with other disease markers) and to monitor antiviral treatment.