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Recombinant Hepatitis B Surface Antigen (ayw)

Recombinant Hepatitis B Surface Antigen (ayw)

Item no.	DAG528
Manufacturer	Creative Diagnostics
Amount	0.5 mg
Category	Oncology Peptides & Proteins Recombinant Proteins Western Blot ELISA By Organ Hepatic Cancer Immunostaining
Type	Proteins Recombinant
Format	Liquid
Applications	WB, ELISA
Specific against	other
Purity	>95% pure, (SDS-PAGE, Coomassie staining) Purified from broken yeast cells using, clarification, microfiltration, chromatography, gel filtration, ultra filtration, and sterile filtration.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Manufacturer - Applications	Suitable for use in ELISA and Western blot. Each, laboratory should determine an optimum working titer for use in its, particular application. Other applications have not been tested but use in, such assays should not necessarily be excluded.
Storage Conditions	Store at 2–8oC. DO NOT FREEZE!
Full name	Hepatitis B Virus Surface Antigen
Product Overview	Recombinant, Hepatitis B surface antigen, contains full-length HBsAg (226 amino acids, molecular weight of 25.5 kDa), was, expressed in Pichia pastoris, and puried in vitro using Metal affinity, chromatography techniques.
Background - Introduction	Hepatitis, B Virus (HBV) infection induces a disease state which manifests itself in a, variety of ways, characterized by the extent of liver damage, inflammation, and viral persistence. HBV infection is also associated with a 100 fold, increased risk of hepatocellular carcinoma and currently infects over 250, million people worldwide. HBV has a partially double stranded 3.2 kilobase, DNA genome which contains four open reading frames. One of these encodes a, 154 amino acid protein called the HBx protein. HBx has been shown to be a, transcriptional transactivator of both viral and cellular promoters. Lacking, a DNA binding domain and nuclear localization signal, HBx is believed to, exert transcriptional activity through protein protein interaction.
Background - Keywords	HBsAg, Hep B surface antigen, Hepatitis B Virus major surface antigen, Hepatitis B, virus S antigen, Large envelope protein, Large surface protein, LHB, Major, surface antigen, Hepadnaviridae, Orthohepadnavirus
Abbr	HBsAg (ayw)
Manufacturer - Format	Purified, Liquid
Buffer	0.2M, Sodium phosphate, pH7.4 containing 0.03M Sodium chloride
Concentration	1mg/ml
Preservative	None
Antigen Description	HBsAg is the surface, antigen of the Hepatitis-B-Virus (HBV). It indicates current Hepatitis B, infection. The capsid of a virus has different surface proteins from the rest of the, virus which act as antigens. These antigens are recognized by antibody, proteins that bind specifically to one of these surface proteins. Today, these antigen-proteins can be a genetically manufactured (e.g. transgene E. coli) to produce material for a simple antigen test, which detects the, presence of HBV. It is present in the sera of patients with viral hepatitis B, (with or without clinical symptoms). Patients who developed antibodies, against HBsAg (anti-HBsAg seroconversion) are usually considered, non-infectious. HBsAg detection by immunoassay is used in blood screening, to, establish a diagnosis of hepatitis B infection in the clinical setting (in, combination with other disease markers) and to monitor antiviral treatment.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 12/25/2025

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