ERCC2 Antibody

ArtNr	CSB-PA007770ESR2HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Transcription Factors Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TFIIH 80 kDa subunit antibody; Basic transcription factor 2 80 kDa subunit antibody; BTF2 p80 antibody; COFS 2 antibody; COFS2 antibody; CXPD antibody; DNA excision repair protein ERCC 2 antibody; DNA excision repair protein ERCC-2 antibody; DNA repair protein complementing XP D cells antibody; DNA repair protein complementing XP-D cells antibody; EM9 antibody; ERCC 2 antibody; ERCC2 antibody; ERCC2_HUMAN antibody; Excision repair 2 antibody; Excision repair cross complementing rodent repair deficiency complementation antibody; Excision repair cross complementing rodent repair deficiency; complementation group 2 antibody; MAG antibody; MGC102762 antibody; MGC126218 antibody; MGC126219 antibody; OTTHUMP00000045860 antibody; OTTHUMP00000045861 antibody; OTTHUMP00000045862 antibody; OTTHUMP00000045863 antibody; TFIIH 80 kDa subunit antibody; TFIIH basal transcription factor complex 80 kDa subunit antibody; TFIIH Basal Transcription Factor Complex Helicase Subunit antibody; TFIIH basal transcription factor complex helicase XPD subunit antibody; TFIIH basal transcription factor complex p80 subunit antibody; TFIIH p80 antibody; TTD antibody; Xeroderma pigmentosum complementary group D antibody; Xeroderma pigmentosum group D complementing protein antibody; Xeroderma pigmentosum group D-complementing protein antibody; XPD antibody; XPDC antibody
Similar products	ERCC2, XPD XPDC, General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFII
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	ERCC2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	TFIIH 80 kDa subunit antibody; Basic transcription factor 2 80 kDa subunit antibody; BTF2 p80 antibody; COFS 2 antibody; COFS2 antibody; CXPD antibody; DNA excision repair protein ERCC 2 antibody; DNA excision repair protein ERCC-2 antibody; DNA repair protein complementing XP D cells antibody; DNA repair protein complementing XP-D cells antibody; EM9 antibody; ERCC 2 antibody; ERCC2 antibody; ERCC2_HUMAN antibody; Excision repair 2 antibody; Excision repair cross complementing rodent repair deficiency complementation antibody; Excision repair cross complementing rodent repair deficiency; complementation group 2 antibody; MAG antibody; MGC102762 antibody; MGC126218 antibody; MGC126219 antibody; OTTHUMP00000045860 antibody; OTTHUMP00000045861 antibody; OTTHUMP00000045862 antibody; OTTHUMP00000045863 antibody; TFIIH 80 kDa subunit antibody; TFIIH basal transcription factor complex 80 kDa subunit antibody; TFIIH Basal Transcription Factor Complex Helicase Subunit antibody; TFIIH basal transcription factor complex helicase XPD subunit antibody; TFIIH basal transcription factor complex p80 subunit antibody; TFIIH p80 antibody; TTD antibody; Xeroderma pigmentosum complementary group D antibody; Xeroderma pigmentosum group D complementing protein antibody; Xeroderma pigmentosum group D-complementing protein antibody; XPD antibody; XPDC antibody
Immunogen Species	Human
Immunogen	Recombinant Human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:2000 IHC:1:20-1:200
Background	ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300AA)
Clonality	Polyclonal

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