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GRB7 Antibody

ArtNr CSB-PA009890ESR2HU-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias B47 antibody,Epidermal growth factor receptor GRB 7 antibody,Epidermal growth factor receptor GRB-7 antibody,GRB7 adapter protein antibody,GRB7 antibody,GRB7_HUMAN antibody,Growth factor receptor bound protein 7 antibody,Growth factor receptor-bound protein 7 antibody,OTTHUMP00000164349 antibody,OTTHUMP00000164350 antibody,OTTHUMP00000164351 antibody,OTTHUMP00000164352 antibody
Similar products GRB7, Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
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Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Manufacturer - Targets
GRB7
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
B47 antibody, Epidermal growth factor receptor GRB 7 antibody, Epidermal growth factor receptor GRB-7 antibody, GRB7 adapter protein antibody, GRB7 antibody, GRB7_HUMAN antibody, Growth factor receptor bound protein 7 antibody, Growth factor receptor-bound protein 7 antibody, OTTHUMP00000164349 antibody, OTTHUMP00000164350 antibody, OTTHUMP00000164351 antibody, OTTHUMP00000164352 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Growth factor receptor-bound protein 7 protein (233-532AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
Background
Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purified
General Research Areas
Signal Transduction
Initial Research Areas
Signal Transduction
Antigen Species
Human
Antigen
Recombinant Human Growth factor receptor-bound protein 7 protein (233-532AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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