IRF8 Antibody

ArtNr	CSB-PA011823ESR2HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Antibodies By Cell Type Melanoma Immunohistochemistry ELISA Primary Antibodies Glial Cell Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	H ICSBP antibody; H-ICSBP antibody; HGNC:5358 antibody; HICSBP antibody; ICSBP 1 antibody; ICSBP antibody; ICSBP1 antibody; Interferon consensus sequence binding protein 1 antibody; Interferon consensus sequence binding protein antibody; Interferon consensus sequence-binding protein antibody; Interferon regulatory factor 8 antibody; IRF 8 antibody; IRF-8 antibody; Irf8 antibody; IRF8_HUMAN antibody; MYLS antibody
Similar products	IRF8, ICSBP1, Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	IRF8
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	H ICSBP antibody; H-ICSBP antibody; HGNC:5358 antibody; HICSBP antibody; ICSBP 1 antibody; ICSBP antibody; ICSBP1 antibody; Interferon consensus sequence binding protein 1 antibody; Interferon consensus sequence binding protein antibody; Interferon consensus sequence-binding protein antibody; Interferon regulatory factor 8 antibody; IRF 8 antibody; IRF-8 antibody; Irf8 antibody; IRF8_HUMAN antibody; MYLS antibody
Immunogen Species	Human
Immunogen	Recombinant Human Interferon regulatory factor 8 protein (137-426AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200
Background	Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Interferon regulatory factor 8 protein (137-426AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ul

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Lieferung vsl. bis 14.08.2025

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