SMAD3 Antibody

ArtNr	CSB-PA021788ESR2HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Colorectal Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IP, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZP586N0721 antibody,DKFZp686J10186 antibody,hMAD 3 antibody,hMAD-3 antibody,hSMAD3 antibody,HSPC193 antibody,HST17436 antibody,JV15 2 antibody,JV15-2 antibody,JV152 antibody,LDS1C antibody,LDS3 antibody,MAD (mothers against decapentaplegic Drosophila) homolog 3 antibody,MAD homolog 3 antibody,Mad homolog JV15 2 antibody,Mad protein homolog antibody,MAD,mothers against decapentaplegic homolog 3 antibody,Mad3 antibody,MADH 3 antibody,MADH3 antibody,MGC60396 antibody,Mothers against decapentaplegic homolog 3 antibody,Mothers against DPP homolog 3 antibody,SMA and MAD related protein 3 antibody,SMAD 3 antibody,SMAD antibody,SMAD family member 3 antibody,SMAD,mothers against DPP homolog 3 antibody,Smad3 antibody,SMAD3_HUMAN antibody
Similar products	SMAD3, MADH3, Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:500, IF:1:50-1:200, IP:1:200-1:2000
Manufacturer - Targets	SMAD3
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	DKFZP586N0721 antibody, DKFZp686J10186 antibody, hMAD 3 antibody, hMAD-3 antibody, hSMAD3 antibody, HSPC193 antibody, HST17436 antibody, JV15 2 antibody, JV15-2 antibody, JV152 antibody, LDS1C antibody, LDS3 antibody, MAD (mothers against decapentaplegic Drosophila) homolog 3 antibody, MAD homolog 3 antibody, Mad homolog JV15 2 antibody, Mad protein homolog antibody, MAD, mothers against decapentaplegic homolog 3 antibody, Mad3 antibody, MADH 3 antibody, MADH3 antibody, MGC60396 antibody, Mothers against decapentaplegic homolog 3 antibody, Mothers against DPP homolog 3 antibody, SMA and MAD related protein 3 antibody, SMAD 3 antibody, SMAD antibody, SMAD family member 3 antibody, SMAD, mothers against DPP homolog 3 antibody, Smad3 antibody, SMAD3_HUMAN antibody
Immunogen Species	Human
Immunogen	Recombinant Human Mothers against decapentaplegic homolog 3 protein (1-230AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:500 IF:1:50-1:200 IP:1:200-1:2000
Background	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Antigen Species	Human
Antigen	Recombinant Human Mothers against decapentaplegic homolog 3 protein (1-230AA)
Clonality	Polyclonal

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Menge: 50 ul

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Lieferung vsl. bis 18.12.2025