STAMBP Antibody

ArtNr	CSB-PA022794HA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AMSH antibody,Associated molecule with the SH3 domain of STAM antibody,Endosome associated ubiquitin isopeptidase antibody,Endosome-associated ubiquitin isopeptidase antibody,MGC126516 antibody,MGC126518 antibody,MICCAP antibody,STABP_HUMAN antibody,STAM binding protein antibody,STAM-binding protein antibody,Stambp antibody
Similar products	STAMBP, AMSH, STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Manufacturer - Targets	STAMBP
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	AMSH antibody, Associated molecule with the SH3 domain of STAM antibody, Endosome associated ubiquitin isopeptidase antibody, Endosome-associated ubiquitin isopeptidase antibody, MGC126516 antibody, MGC126518 antibody, MICCAP antibody, STABP_HUMAN antibody, STAM binding protein antibody, STAM-binding protein antibody, Stambp antibody
Immunogen Species	Human
Immunogen	Recombinant Human STAM-binding protein (1-424AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:200
Background	Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human STAM-binding protein (1-424AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ug

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Lieferung vsl. bis 29.01.2026

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