NEDD8 Antibody

ArtNr	CSB-PA053660
Hersteller	Cusabio
Menge	100 ul
Kategorie	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FLJ43224 antibody,MGC104393 antibody,MGC125896 antibody,MGC125897 antibody,NED8 antibody,NEDD 8 antibody,NEDD-8 antibody,Nedd8 antibody,NEDD8_HUMAN antibody,Neddylin antibody,Neural precursor cell expressed developmentally down regulated 8 antibody,Neural precursor cell expressed developmentally down regulated gene 8 antibody,Neural precursor cell expressed developmentally down-regulated protein 8 antibody,Rub1 antibody,Ubiquitin like protein Nedd 8 antibody,Ubiquitin like protein Nedd8 antibody,Ubiquitin-like protein Nedd8 antibody
Similar products	NED8, NEDD-8, Ubiquitin-like protein NEDD8
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100
Manufacturer - Targets	NEDD8
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	FLJ43224 antibody, MGC104393 antibody, MGC125896 antibody, MGC125897 antibody, NED8 antibody, NEDD 8 antibody, NEDD-8 antibody, Nedd8 antibody, NEDD8_HUMAN antibody, Neddylin antibody, Neural precursor cell expressed developmentally down regulated 8 antibody, Neural precursor cell expressed developmentally down regulated gene 8 antibody, Neural precursor cell expressed developmentally down-regulated protein 8 antibody, Rub1 antibody, Ubiquitin like protein Nedd 8 antibody, Ubiquitin like protein Nedd8 antibody, Ubiquitin-like protein Nedd8 antibody
Immunogen Species	Human
Immunogen	Synthesized peptide derived from Internal of human NEDD8.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:3000 IHC:1:50-1:100
Background	Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Margaret A. Read, Mol. Cell. Biol., Apr 2000, 20: 2326 - 2333. Kenneth Wu, J. Biol. Chem., Aug 2003, 278: 28882 - 28891. Katsumi Kito, J. Biol. Chem., Jun 2001, 276: 20603 - 20609.
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Synthesized peptide derived from Internal of Human NEDD8.
Clonality	Polyclonal

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Menge: 100 ul

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