Comparison

NEDD8 Antibody

Item no. CSB-PA053660
Manufacturer Cusabio
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias FLJ43224 antibody,MGC104393 antibody,MGC125896 antibody,MGC125897 antibody,NED8 antibody,NEDD 8 antibody,NEDD-8 antibody,Nedd8 antibody,NEDD8_HUMAN antibody,Neddylin antibody,Neural precursor cell expressed developmentally down regulated 8 antibody,Neural precursor cell expressed developmentally down regulated gene 8 antibody,Neural precursor cell expressed developmentally down-regulated protein 8 antibody,Rub1 antibody,Ubiquitin like protein Nedd 8 antibody,Ubiquitin like protein Nedd8 antibody,Ubiquitin-like protein Nedd8 antibody
Similar products NED8, NEDD-8, Ubiquitin-like protein NEDD8
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100
Manufacturer - Targets
NEDD8
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
FLJ43224 antibody, MGC104393 antibody, MGC125896 antibody, MGC125897 antibody, NED8 antibody, NEDD 8 antibody, NEDD-8 antibody, Nedd8 antibody, NEDD8_HUMAN antibody, Neddylin antibody, Neural precursor cell expressed developmentally down regulated 8 antibody, Neural precursor cell expressed developmentally down regulated gene 8 antibody, Neural precursor cell expressed developmentally down-regulated protein 8 antibody, Rub1 antibody, Ubiquitin like protein Nedd 8 antibody, Ubiquitin like protein Nedd8 antibody, Ubiquitin-like protein Nedd8 antibody
Immunogen Species
Human
Immunogen
Synthesized peptide derived from Internal of human NEDD8.
Dilution
ELISA:1:2000-1:10000
WB:1:500-1:3000
IHC:1:50-1:100
Background
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Margaret A. Read, Mol. Cell. Biol., Apr 2000, 20: 2326 - 2333.
Kenneth Wu, J. Biol. Chem., Aug 2003, 278: 28882 - 28891.
Katsumi Kito, J. Biol. Chem., Jun 2001, 276: 20603 - 20609.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Synthesized peptide derived from Internal of Human NEDD8.
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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