MMP2 Antibody

MMP2

72 kDa gelatinase antibody; 72kD type IV collagenase antibody; CLG 4 antibody; CLG 4A antibody; CLG4 antibody; CLG4A antibody; Collagenase Type 4 alpha antibody; Collagenase type IV A antibody; Gelatinase A antibody; Gelatinase alpha antibody; Gelatinase neutrophil antibody; Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody; Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) antibody; Matrix Metalloproteinase 2 antibody; Matrix metalloproteinase II antibody; Matrix metalloproteinase-2 antibody; MMP 2 antibody; MMP II antibody; MMP-2 antibody; MMP2 antibody; MMP2_HUMAN antibody; MONA antibody; Neutrophil gelatinase antibody; PEX antibody; TBE 1 antibody; TBE-1 antibody

Recombinant Human 72 kDa type IV collagenase protein (445-660AA)

Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.

>95%, Protein G purified

Cardiovascular

Recombinant Human 72 kDa type IV collagenase protein (445-660AA)