ArtNr |
CSB-PA356939LA01HMN-50ug |
Hersteller |
Cusabio
|
Menge |
50 ug |
Quantity options |
100 ug
20 ug
50 ug
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human (Homo sapiens) |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
L2 antibody; Minor capsid protein L2 antibody |
Similar products |
L2, Minor capsid protein L2 |
Lieferbar |
|
Specificity |
Human papillomavirus type 18 |
Manufacturer - Type |
Polyclonal Antibody |
Manufacturer - Targets |
L2 |
Storage Conditions |
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Immunogen Species |
Human papillomavirus type 18 |
Immunogen |
Recombinant Human papillomavirus type 18 Minor capsid protein L2 protein (1-462AA) |
Background |
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, escorts the genomic DNA into the nucleus, in particular by promoting virion endosomal escape. It is involved, through its interaction with host dynein, in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. Mediates the viral genome import into the nucleus through binding to host importins. Mediates the viral genome import into the nucleus through binding to host importins. Once within the nucleus, L2 localizes viral genomes to PML bodies in order to activate early gene expression for establishment of infection. Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions. During virion assembly, encapsidates the genome by direct interaction with the viral DNA (By similarity). |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Others |
Antigen Species |
Human papillomavirus type 18 |
Antigen |
Recombinant Human papillomavirus type 18 Minor capsid protein L2 protein (1-462AA) |
Clonality |
Polyclonal |
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