PRKAB2 Antibody

Polyclonal Antibody

PRKAB2

5' AMP activated protein kinase beta 2 subunit antibody, 5' AMP activated protein kinase subunit beta 2 antibody, 5''-AMP-activated protein kinase subunit beta-2 antibody, AAKB2_HUMAN antibody, AMP activated protein kinase beta 2 non catalytic subunit antibody, AMPK beta 2 antibody, AMPK beta 2 chain antibody, AMPK subunit beta 2 antibody, AMPK subunit beta-2 antibody, MGC61468 antibody, PRKAB 2 antibody, Prkab2 antibody, Protein kinase AMP activated beta 2 non catalytic subunit antibody

Recombinant Human 5'-AMP-activated protein kinase subunit beta-2 protein (1-272AA)

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Antigen Affinity Purified

Cardiovascular

Recombinant Human 5\\\'-AMP-activated protein kinase subunit beta-2 protein (1-272AA)